"How to stop a running nose" A running nose can be quite bothersome, but there are steps you can take to find relief. Stay hydrated by drinking plenty of fluids. Use a saline nasal spray or rinse to help clear nasal passages. Over-the-counter decongestants or antihistamines may provide temporary relief. Use a humidifier or inhale steam to moisturize nasal passages. Avoid irritants like smoke or strong odors. If symptoms persist or worsen, it's best to consult a healthcare professional for further evaluation and treatment.